How to change the default audio in Wine to Alsa only

I am aware that wine has just undergone a complete rewrite of the audio system and maybe winetricks could still help with your question...

In a terminal run

winetricks

In your terminal type winetricks sound=alsa.

This does the same effect as in @fossfreedom-s solution. Note: if you want to disable all audio in wine, use winetricks sound=disabled.

1. Open a terminal and run regedit.
2. Go to HKEY_CURRENT_USER\Software\Wine\Drivers
3. Set Audio to alsa

To restore Ubuntu's default value, repeat the first 2 steps and then set Audio to pulse.

that can be done via winetricks also:

winetricks settings sound=alsa

to see all available options:

winetricks settings list | grep sound

Another way is running gstreamer-properties and selecting ALSA, OSS or PulseAudio in the Default Output and Default Input options. Whichever option the user prefers. Works like the winetricks mentioned by fossfreedom but this is only for sound in general. In his case you can do a lot more.