Changing A value on Time Column with Python/Pandas

If need only 00 hours solution is simplier/ faster with Series.dt.floor :

task_df["TARGET_END_DATE"] = task_df["TARGET_END_DATE"].dt.floor('d')

If need some hour, e.g. 10:00 add it:

task_df["TARGET_END_DATE"] = (task_df["TARGET_END_DATE"].dt.floor('d') + 
                                pd.Timedelta(10, 'hour'))

You can use:

task_df["TARGET_END_DATE"].dt.normalize()

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