How to change xorg.conf file with permission?

Open a Terminal and then :

Open with Gedit...

gksudo gedit /etc/X11/xorg.conf

open with nano...

sudo nano /etc/X11/xorg.conf

now you can edit ..

P.D make a backup before change the file so you can revert your modification...

sudo cp /etc/X11/xorg.conf /etc/X11/xorg.conf_backup

Probably you're trying to edit the file without permissions. First make a backup of your file in case something goes wrong.

sudo cp /etc/X11/xorg.conf{,.bk}

Then, you can edit the file with you text editor, for example

gksudo gedit /etc/X11/xorg.conf

And save it.