Can I rebind mouse buttons to keys?
Currently, you cannot remap the mouse buttons away from the primary/secondary skills. You can use Elective Mode (Options > Gameplay > Check Elective Mode) to move any skills (including primary/secondary) to keys 1-4, but you can only remap those keys. Therefore, if you want to avoid using the mouse for skills, you will be limited to only 4 skills.
I used autohotkey to bind key buttons to keys. Here's my script:
q::MouseClick
+q::MouseClick
w::MouseClick, right
+w::MouseClick, right