How do you pronounce, "pleurisy"?
As pertains to the second question The Longman Pronunciation dictionary has this.
pleurisy 'plʊər əs i||'plʊr əs i
This means that in BrE jod is not normally used and that in Gen Am not only jod but as well the diphthong disappears. Therefore, what would be a (the) mainstream pronunciation in Gen Am is not as "boor, spoor,…".