genymotion throws libssl_conf.so: cannot open shared object file: No such file or directory

I think you have the answer just write

export OPENSSL_CONF=/etc/ssl/

to your .bashrc file and restart your computer The problem should be permanently solved.

I had a similar issue installing GenomeBrowser on Fedora and this solved it.

you could achieve the above by:

echo "export OPENSSL_CONF=/etc/ssl/" >> ~/.bashrc && source ~/.bashrc 

or if you have zsh for your shell you could do this instead:

echo "export OPENSSL_CONF=/etc/ssl/" >> ~/.zshrc && source ~/.zshrc