Outlook 2010: Your Outlook data file cannot be configured C:\Users\<username>.<domain>\AppData\Local\Microsoft\Outlook\outlook2.ost?

Reset it with the E-mail configurator.

You can find it in Control panel > User Accounts > E-mail >

  • If the Outlook data file is synchronized with Exchange, then turn off 'cached modus' in the account settings, renew the Outlook profile, and turn 'cached modus' back on.
  • If the Outlook data file is stand-alone, then update its location with the Data files option.

See also: Error 0x8004010F in Outlook 2010


Ensure that the path to the .ost file that Outlook is looking for exists and is writeable by the user. In my case I achieved this using mklink /j to make the profile visible under the previous path.