Difference between consecutive elements in list [duplicate]

You could utilize enumerate, zip and list comprehensions:

>>> a = [0, 4, 10, 100]

# basic enumerate without condition:
>>> [x - a[i - 1] for i, x in enumerate(a)][1:]
[4, 6, 90]

# enumerate with conditional inside the list comprehension:
>>> [x - a[i - 1] for i, x in enumerate(a) if i > 0]
[4, 6, 90]

# the zip version seems more concise and elegant:
>>> [t - s for s, t in zip(a, a[1:])]
[4, 6, 90]

Performance-wise, there seems to be not too much variance:

In [5]: %timeit [x - a[i - 1] for i, x in enumerate(a)][1:]
1000000 loops, best of 3: 1.34 µs per loop

In [6]: %timeit [x - a[i - 1] for i, x in enumerate(a) if i > 0]
1000000 loops, best of 3: 1.11 µs per loop

In [7]: %timeit [t - s for s, t in zip(a, a[1:])]
1000000 loops, best of 3: 1.1 µs per loop

Use the recipe for pairwise from the itertools documentation:

from itertools import izip, tee
def pairwise(iterable):
    "s -> (s0,s1), (s1,s2), (s2, s3), ..."
    a, b = tee(iterable)
    next(b, None)
    return izip(a, b)

Use it like this:

>>> a = [0, 4, 10, 100]
>>> [y-x for x,y in pairwise(a)]
[4, 6, 90]

[x - a[i-1] if i else None for i, x in enumerate(a)][1:]