Punctuation marks [closed]

Your sentence:

Please first look at our wiki space or contact your local site-ops before opening a ticket, if you would like us to look into an issue, or have a change request, please open a JIRA ticket.

As it is, your sentence is both a comma splice and a run-on sentence. Let's punctuate it a little better. That involves changing a run-on sentence into two separate sentences.

Before opening a ticket, please look first at our wiki space or contact your local site-ops. If you would like us to look into an issue, or you would like to submit [better word than have?] a change request, please open a JIRA ticket.

There are other--and perhaps preferable--ways to punctuate your instructions, but my suggestion is perhaps as good as any.