Are there an infinite number of prime quadruples of the form $10n + 1$, $10n + 3$, $10n + 7$, $10n + 9$?
I suppose, you will not find a proof for neither the positive nor the negative result here.
The positive result would obviously imply the (unproven and presumably difficult) twin prime conjecture.
The negative result would disprove the first Hardy-Littlewood conjecture about the density of prime sets with a given pattern, which (among other things) conjectures a (positive) density for prime quadruples.