The feature you are using is not part of ES6. It's the class fields proposal. It allows you to initialize instance properties without having to write a constructor. I.e. your code:

class MyClass {

    myMethod = () => {
        this.myVariable++;
    }

}

is exactly the same as

class MyClass {

    constructor() {
        this.myMethod = () => {
            this.myVariable++;
        };
    }

}

And this also shows you what the difference is between a normal class method an a method created via a class field:

  • A normal method is shared between all instances of the class (it is defined on the prototype)
  • A "class field method" is created per instance

So all the same as reasons as presented in Use of 'prototype' vs. 'this' in JavaScript? apply, but in short:

  • Use "class field methods" if you need a method per instance. Such is the case for event handlers that need to access the current instance. Access to this also only works if you are using an arrow function.
  • Use normal class methods in all other cases.