Recommendation for genealogy software for OS X?

Solution 1:

I haven’t found one that interfaces with the website you mentioned, but here’s a good overview of genealogy software for OS X: http://www.macgenealogy.org/mac-genealogy-software/

MacFamilyTree 6 is actively developed (it was just updated a few days ago), is fully GEDCOM-compatible, and it has an iOS version too!

It doesn’t export to ancestry.com but it can interface with a custom-built website called MacFamilyTree.com.

Solution 2:

I have tried many, and my favourite is iFamily, which is weirdly called iFamily for Leopard as it's full name, but it works fine in Lion.

It had full GEDCOM support, and the only demo limitation is the lack of export to GEDCOM, so you can try it in full more or less without buying.

Solution 3:

You can try 'Reunion', which has GEDCOM import/export and is available for iPad and iPhone too.