How to check if a registry value exists using C#?

For Registry Key you can check if it is null after getting it. It will be, if it doesn't exist.

For Registry Value you can get names of Values for the current key and check if this array contains the needed Value name.

Example:

public static bool checkMachineType()
{    
    RegistryKey winLogonKey = Registry.LocalMachine.OpenSubKey(@"System\CurrentControlSet\services\pcmcia", true);
    return (winLogonKey.GetValueNames().Contains("Start"));
}

public static bool RegistryValueExists(string hive_HKLM_or_HKCU, string registryRoot, string valueName)
{
    RegistryKey root;
    switch (hive_HKLM_or_HKCU.ToUpper())
    {
        case "HKLM":
            root = Registry.LocalMachine.OpenSubKey(registryRoot, false);
            break;
        case "HKCU":
            root = Registry.CurrentUser.OpenSubKey(registryRoot, false);
            break;
        default:
            throw new System.InvalidOperationException("parameter registryRoot must be either \"HKLM\" or \"HKCU\"");
    }

    return root.GetValue(valueName) != null;
}

string keyName=@"HKEY_LOCAL_MACHINE\System\CurrentControlSet\services\pcmcia";
string valueName="Start";
if (Registry.GetValue(keyName, valueName, null) == null)
{
     //code if key Not Exist
}
else
{
     //code if key Exist
}

  RegistryKey rkSubKey = Registry.CurrentUser.OpenSubKey(" Your Registry Key Location", false);
        if (rkSubKey == null)
        {
           // It doesn't exist
        }
        else
        {
           // It exists and do something if you want to
         }

Of course, "Fagner Antunes Dornelles" is correct in its answer. But it seems to me that it is worth checking the registry branch itself in addition, or be sure of the part that is exactly there.

For example ("dirty hack"), i need to establish trust in the RMS infrastructure, otherwise when i open Word or Excel documents, i will be prompted for "Active Directory Rights Management Services". Here's how i can add remote trust to me servers in the enterprise infrastructure.

foreach (var strServer in listServer)
{
    try
    {
        RegistryKey regCurrentUser = Registry.CurrentUser.OpenSubKey($"Software\\Classes\\Local Settings\\Software\\Microsoft\\MSIPC\\{strServer}", false);
        if (regCurrentUser == null)
            throw new ApplicationException("Not found registry SubKey ...");
        if (regCurrentUser.GetValueNames().Contains("UserConsent") == false)
            throw new ApplicationException("Not found value in SubKey ...");
    }
    catch (ApplicationException appEx)
    {
        Console.WriteLine(appEx);
        try
        {
            RegistryKey regCurrentUser = Registry.CurrentUser.OpenSubKey($"Software\\Classes\\Local Settings\\Software\\Microsoft\\MSIPC", true);
            RegistryKey newKey = regCurrentUser.CreateSubKey(strServer, true);
            newKey.SetValue("UserConsent", 1, RegistryValueKind.DWord);
        }
        catch(Exception ex)
        {
            Console.WriteLine($"{ex} - a terrible mistake ...");
        }
    }
}