Angular 2 provides good support for uploading files. No third party library is required.

<input type="file" (change)="fileChange($event)" placeholder="Upload file" accept=".pdf,.doc,.docx">
fileChange(event) {
    let fileList: FileList = event.target.files;
    if(fileList.length > 0) {
        let file: File = fileList[0];
        let formData:FormData = new FormData();
        formData.append('uploadFile', file, file.name);
        let headers = new Headers();
        /** In Angular 5, including the header Content-Type can invalidate your request */
        headers.append('Content-Type', 'multipart/form-data');
        headers.append('Accept', 'application/json');
        let options = new RequestOptions({ headers: headers });
        this.http.post(`${this.apiEndPoint}`, formData, options)
            .map(res => res.json())
            .catch(error => Observable.throw(error))
            .subscribe(
                data => console.log('success'),
                error => console.log(error)
            )
    }
}

using @angular/core": "~2.0.0" and @angular/http: "~2.0.0"


From the answers above I build this with Angular 5.x

Just call uploadFile(url, file).subscribe() to trigger an upload

import { Injectable } from '@angular/core';
import {HttpClient, HttpParams, HttpRequest, HttpEvent} from '@angular/common/http';
import {Observable} from "rxjs";

@Injectable()
export class UploadService {

  constructor(private http: HttpClient) { }

  // file from event.target.files[0]
  uploadFile(url: string, file: File): Observable<HttpEvent<any>> {

    let formData = new FormData();
    formData.append('upload', file);

    let params = new HttpParams();

    const options = {
      params: params,
      reportProgress: true,
    };

    const req = new HttpRequest('POST', url, formData, options);
    return this.http.request(req);
  }
}

Use it like this in your component

  // At the drag drop area
  // (drop)="onDropFile($event)"
  onDropFile(event: DragEvent) {
    event.preventDefault();
    this.uploadFile(event.dataTransfer.files);
  }

  // At the drag drop area
  // (dragover)="onDragOverFile($event)"
  onDragOverFile(event) {
    event.stopPropagation();
    event.preventDefault();
  }

  // At the file input element
  // (change)="selectFile($event)"
  selectFile(event) {
    this.uploadFile(event.target.files);
  }

  uploadFile(files: FileList) {
    if (files.length == 0) {
      console.log("No file selected!");
      return

    }
    let file: File = files[0];

    this.upload.uploadFile(this.appCfg.baseUrl + "/api/flash/upload", file)
      .subscribe(
        event => {
          if (event.type == HttpEventType.UploadProgress) {
            const percentDone = Math.round(100 * event.loaded / event.total);
            console.log(`File is ${percentDone}% loaded.`);
          } else if (event instanceof HttpResponse) {
            console.log('File is completely loaded!');
          }
        },
        (err) => {
          console.log("Upload Error:", err);
        }, () => {
          console.log("Upload done");
        }
      )
  }