If a power of 2 divides a number, under what conditions does it divide a binomial coefficient involving the number that it divides?
This is a comment, but a little long comment.
Recall the definition of the $2-$adic valuation of $n,$ $\nu _2(n),$ meaning the biggest exponent of $2$ that divides $n.$
Your problem, then, can be stated as $s\leq \nu _2(n)$ implies $s\leq \nu _2 \left( \binom{n}{k}\right ).$ From legendre's theorem (i.e., $\nu _2(n!)=n-S_2(n)$ where $S_2(n)$ is the sum of the $1$'s in the $2-$adic expansion of $n$) is not hard to show that
$$\nu _2 \left( \binom{n}{k}\right )=n-S_2(n)-(k-S_2(k))-(n-k-S_2(n-k))=S_2(n-k)+S_2(k)-S_2(n).$$ and $$\nu _2(n)=\nu_2(n!)-\nu _2((n-1)!)=1+S_2(n-1)-S_2(n).$$
So your proposition becomes
$s-1\leq S_2(n-1)-S_2(n)$ implies $s\leq S_2(n-k)+S_2(k)-S_2(n).$
this can be, at least, be satisfied if $S_2(n-1)+1\leq S_2(n-k)+S_2(k).$ This is trivial if $k=1.$ For example, if $n$ is odd, this is equivalent to $S_2(n)\leq S_2(n-k)+S_2(k)$ which is always the case, for example if the expansion of $k$ has $1'$s where there is a $1$ in the expansion of $n.$
With the very helpful tip from user BillyJoe, we can say that for any prime $p$,
$$\tag{1} \binom{n}{k} \equiv \left\langle {n_{s-1}\cdots n_0 \atop k_{s-1}\cdots k_0} \right\rangle \prod_{j=1}^{r-s+1}\left\langle {n_{j+s-1}\cdots n_j \atop k_{j+s-1}\cdots k_j} \right\rangle\left\langle {n_{j+s-2}\cdots n_j \atop k_{j+s-2}\cdots _j} \right\rangle^{-1} \left( \textrm{mod} ~ p^s \right), $$
where the indices 0 and $r$ represent the terms corresponding to the lowest and highest powers (respectively) in the $p$-adic expansions of $n$ and $k$, and the angular brackets correspond to a slight modification (described in more detail here) of the ordinary binomial coefficient symbols.
We then have that:
$$ \left\langle {n_{s-1}\cdots n_0 \atop k_{s-1}\cdots k_0} \right\rangle \prod_{j=1}^{r-s+1}\left\langle {n_{j+s-1}\cdots n_j \atop k_{j+s-1}\cdots k_j} \right\rangle\left\langle {n_{j+s-2}\cdots n_j \atop k_{j+s-2}\cdots _j} \right\rangle^{-1} \equiv 0 \left( \textrm{mod} ~ p^s \right),\tag{2} $$
if and only if $p^s \mid \binom{n}{k}$.
We therefore have a general condition for when $p^s$ divides $\binom{n}{k}$, whether or not $p^s \mid n$.
For the special case where $p=2$ and $2^s \mid n$, which was the premise of the original question, we may be able to get a cleaner expression than what I have above in Eq. 2.