When should I ever use file.read() or file.readlines()?

Solution 1:

The short answer to your question is that each of these three methods of reading bits of a file have different use cases. As noted above, f.read() reads the file as an individual string, and so allows relatively easy file-wide manipulations, such as a file-wide regex search or substitution.

f.readline() reads a single line of the file, allowing the user to parse a single line without necessarily reading the entire file. Using f.readline() also allows easier application of logic in reading the file than a complete line by line iteration, such as when a file changes format partway through.

Using the syntax for line in f: allows the user to iterate over the file line by line as noted in the question.

(As noted in the other answer, this documentation is a very good read):

https://docs.python.org/3/tutorial/inputoutput.html#methods-of-file-objects

Note: It was previously claimed that f.readline() could be used to skip a line during a for loop iteration. However, this doesn't work in Python 2.7, and is perhaps a questionable practice, so this claim has been removed.

Solution 2:

Hope this helps!

https://docs.python.org/2/tutorial/inputoutput.html#methods-of-file-objects

When size is omitted or negative, the entire contents of the file will be read and returned; it’s your problem if the file is twice as large as your machine’s memory

Sorry for all the edits!

For reading lines from a file, you can loop over the file object. This is memory efficient, fast, and leads to simple code:

for line in f:
    print line,

This is the first line of the file.
Second line of the file