Lodash : how to do a case insensitive sorting on a collection using orderBy?

The documentation specifies that you can pass a function as "iteratee":

[iteratees=[_.identity]] (Array[]|Function[]|Object[]|string[]): The iteratees to sort by.

So you can do

const users = [
  { name: 'A', age: 48 },
  { name: 'B', age: 34 },
  { name: 'b', age: 40 },
  { name: 'a', age: 36 }
];

const sortedUsers = _.orderBy(users, [user => user.name.toLowerCase()], ['desc']);
console.log(sortedUsers);
<script src="https://cdn.jsdelivr.net/lodash/4.13.1/lodash.min.js"></script>

Ordering by multiple properties:

const users = [
  { name: 'A', age: 48 },
  { name: 'B', age: 34 },
  { name: 'b', age: 40 },
  { name: 'a', age: 36 }
]

const nameSorter = user => user.name.toLowerCase()
const ageSorter = 'age'

const sortedUsers = _.orderBy(users, [nameSorter, ageSorter], ['desc', 'asc'])

You can combine Felix Kling example with _.get function to sort by dynamic nested attributes:

const _ = require('lodash');

let test = [{ a: {b:'AA'}},{a: {b:'BB'} }, {a: {b: 'bb'}}, {a:{b:'aa'}}];

let attrPath = 'a.b';

_.orderBy(test, [item => _.get(item, attrPath).toLowerCase()]);