Pinging Mac "computername" hits strange IP address
Solution 1:
Akamai runs a content distributions system used by major websites to provide fast web response on a global scale. It is used by Apple, Adobe, Microsoft and many others.
Port 443 is used for HTTPS - the encrypted version of HTTP web-page access.
It is quite normal to see a lot of traffic directed through Akamai.
iCloud content is stored on Akamai servers. Assuming you are using iCloud, e.g. to store Safari bookmarks, it is normal that opening Safari triggers a connection to Akamai since the actual content (= Safari bookmarks) is physically stored on Akamai distribution servers and needs to be synced when opening the browser.
More insight on it:
On July 21, 1999, at Macworld Expo New York, Apple and Akamai announced a strategic partnership to build Apple's new media network, QuickTime TV (QTV), based on QuickTime Streaming Server.[32] Both companies later announced that Apple had made a $12.5 million investment in the company the previous month.[33] Apple continues to use Akamai as their primary content delivery network[34] for a wide range of applications including software downloads from Apple's Website, QuickTime movie trailers, and the iTunes Store.[35]
So to your question "is this possibly a symptom of having been compromised or virus/malware infected?" - I don't think it is compromised or infected by virus.