Chrome on MacOS started rejecting self-signed certificates
Try to run the following command from the terminal and relaunch Chrome
defaults write com.google.Chrome EnableCommonNameFallbackForLocalAnchors -bool true
This can help you to solve your issue.
Or
If you need a workaround to get the site working without replacing the certificate you can do the following.
- Download the certificate from the server (using another browser or with openssl)
- Install the certificate into Keychain Access under the login store
- Set the certificate to "always trust" by double clicking on it once it's been installed.