How to remove the "Go to live visual tree" / "Enable selection" / "Display layout adorners" overlay when debugging?

Solution 1:

Just simply uncheck Tools -> Options -> Debugging -> General -> Enable UI Debugging Tools for XAML -> Show runtime tools in application.

Screenshot

Solution 2:

Just uncheck "Show runtime tools in application"

Settings option to toggle

A quicker alternative can be found in a toggle on the Live Visual Tree pane.

Live Visual Tree pane toggle