Does $f$ have a critical point if $f(x, y) \to +\infty$ on all horizontal lines and $f(x, y) \to -\infty$ on all vertical lines?
Solution 1:
No, a function like this need not have a critical point. However, the only example I could find is a bit complicated and unfortunately not explicit. With a bit of work, one could make this explicit, but it would not be pretty. There should be a simpler example, though...
Let $L$ be the ray from the origin at a $45^\circ$ angle, i.e., defined by $x=y \ge 0$, and let $U$ be the open 1-neighborhood of $L$ in the plane, i.e., all points with distance less than $1$ to $L$. Then there exists a $C^\infty$-diffeomorphism $\phi: U \to U\setminus L$, which is the identity in a neighborhood of $\partial U$. (Note that $U$ and $U\setminus L$ are open sets, and $\phi^{-1}$ obviously does not extend to $L$.) Then we can extend $\phi$ to a $C^\infty$-diffeomorphism $\phi: \mathbb{R}^2 \to \mathbb{R}^2 \setminus L$ by defining it to be the identity outside $U$.
Now let $g(x,y) = x^2-y^2$, which already has the correct limits, but obviously has a critical point at $(0,0)$. Define $f(x,y) = g(\phi(x,y))$. Any horizontal or vertical line either does not intersect $U$ at all, or it intersects it in an interval of length $\le 2\sqrt{2}$, and since $f=g$ outside of $U$, we have that the limits of $f$ and $g$ along horizontal and vertical lines are the same, so $f$ has the desired limits. As a composition of smooth functions, it is smooth, and by the chain rule $f$ does not have any critical points, because $\phi$ does not have any, and the only critical point of $g$ is at $(0,0) \in L$, which is not in the image of $\phi$.
Solution 2:
Think about it as a zero sum game, where the payoff to the $x$ player is $f(x,y)$, and the payoff to the $y$ player is $-f(x,y)$. So $X$ is trying to maximize $f$ and $Y$ is trying to minimize $f$.
Consider, for example, the sets $R_\delta = \{ (x,y) \in \mathbb{R}^2 : ||(x,y)|| \le \delta \}$, or the set of balls based at some other point. Then each player has an upper hemi-continuous best reply to the other player on $R_\delta$, by continuity of $f$ and Berge's Theorem of the Maximum.
If your conjecture is true, there exists a finite $\delta^*$ for which there is a pure-strategy equilibrium to the game with $(x^*,y^*) $ in the interior of $ R_{\delta^*}$. If it is false, either there is no pure strategy equilibrium to the game, or there is a pure-strategy eqm but it is always on the boundary of $R_\delta$ for any $\delta$. By picking a particular fixed-point theorem to get existence of an eqm point, you could then try to reverse engineer sufficient conditions for the conjecture to be true or false.
I am not sure it is either always true or false, since the assumptions are of the "coerciveness" kind: they describe what happens as $x$ or $y$ gets very large, but give no local information. So I can imagine lots of critical points in some neigborhood of, say, zero, and then the function goes off to $\pm \infty$ outside the neighborhood. Conversely, I can imagine that at any critical point in $x$, there is first-order variation in $y$, and vice versa (i.e., one player or the other always wants to ``deviate'' from the proposed $x$ and $y$ even if the other is happy with their strategy, so there is no pure-strategy Nash equilibrium).