Could Autorun Virus, affect my PC via Wine?

Solution 1:

Can viruses run in Wine?

Yes.

Will inserting a CD with an autorun-enabled virus into an Ubuntu+Wine computer lead to the virus being loaded and the computer becoming infected?

No. You could enable that sort of autorun scripting if you really tried, but it's not something Ubuntu ships with.

What happens if you run a virus through Wine?

What happens if you run anything through wine? A virus is just an application that does particular things. If wine supports those things, they're going to work as designed. If wine doesn't, you're going to see a bunch of messy errors.

It's really not possible to give one answer that covers all viruses.
I generally consider it better to just avoid them in the first place.

What does a virus run under Wine have access to?

Having seen another answer claiming that Wine can't hurt anything, I think it's important to add that it's not true. Wine has access to more than enough to ruin your day.

For your convenience, your home directory is symlinked to My Documents. That means you can save things easily from Wine applications but it also means that even a basic virus could, for example, encrypt all your Ubuntu documents and hold them hostage.

Solution 2:

Some viruses will explore all drives. Which means, yes, they can infect your PC. Others only infect the system drive, which sounds bad, but remember, the system drive in Windows is C:/ which is a virtual drive in Wine. But, Wine redirects user folders to your ubuntu folders, so they could have an effect. In other words, your home folder could be infected. It's a Windows virus - it'll target system folders - for the virtual drive, not Ubuntu. Basically, they can do harm, but if they don't outside of the virtual C drive, you can just delete the virtual drive and re-install Wine.