Can't play modded Fallout 4 due to crash to desktop

Here's my problem: I want to play a heavily modded Fallout 4. Once I start a fresh game I can, strangely enough, play just fine without any issues and any crash. However, once I exit the game, and start it up later, I cannot load the save game any more, because it crashes to desktop almost immediately.

The mods I want to play with: https://pastebin.com/gTY2J3Sk
Any culprits there?

Solution 1:

Happend to me as well - solution which worked for me is below.

Targets:

• Avoid reinstall of the game
• Keep all players settings in save untouched

1) Situation description

• Game was modded (> 80 mods), but with fully functional saving system
  • Suddenly without any change in the game or Nexus, the game was crashing to desktop without any information during saving
  • save files were suddenly saved as *.fos.tmp instead of *.f4se and .fos (save files in C:\Users*user\Documents\My Games\Fallout4\Saves)

2) solution, which worked for me (chronologically)

• Created backup of saves
• Switched off all "Plugins" in Nexus (Plugins, not the mods!)
• Splitted "plugins" into 2 halfs and first half switched back on
• Try to save the game and because of OK save process, I splitted the remaining part into 2 halfs and switch of one half only (it means 1/2 + 1/4 of plugins were switched on)
• I was using quicksave for functionality check (quicksave of "original" save)
• With this method was gradually switched on plugins and at the end was identified mod, which suddendly was causing the problem with saving
• At the end I tried to switched on the "problematic" and save was suddenly functional as well, despite that before it was clearly causing the problem

Nevertheless the game is saving again. I hope, that it was helpful for someone.