Is it possible to save in Binding of Isaac?

I know this is kind of silly but is it possible to save current progress? So far I've been leaving the game running so when I return I can attempt to finish the level but it would be nice to just save.

I haven't seen an option in the GUI to save or reload but I figure i'd ask the community. Maybe I am missing something.

No, it's not possible.

The point of the game is to keep short playing sessions where death is a permanent threat. Not having the player be able to save the game both gets across this gameplay idea, and as a nice side effect it keeps players from abusing savegame files or saving mechanics (for example, save and Ctrl+Alt+Del task manager quit the game, and restart).

That said, the overall progress is always saved, such as your general stats and unlocks.

Unlocked characters, stats, and suchlike are saved automatically, but you can't save your progress in a specific session. The game is rather short, and randomly generated each time, so this shouldn't really be a problem.

You play until you die, win, or quit. Then you start over.