Text-To-Speech to read websites in Chrome?

OS X's built in screen reader, VoiceOver, works in Chrome.

To enable it, go to System Preferences-> Universal Access-> Seeing and toggle the VoiceOver: radio group to On. You will also be able to check the shortcut key for easily enabing/disabling VoiceOver.

I recommend you take some time and familiarize yourself with VoiceOver; it's very powerful but takes some getting used to.

Click the VoiceOver Utility button to configure VoiceOver. This lets you change, among many other options, the voice and speaking speed.

enter image description here