Solution 1:

1.Create Uploadfile.aspx

2.Embed the Uploadfile.aspx in Your Html page using iframe

    <%@ Page Language="C#" AutoEventWireup="true" CodeFile="Uploadfile.aspx.cs" Inherits="Uploadfile" %>
    <!DOCTYPE html PUBLIC "-//W3C//DTD XHTML 1.0 Transitional//EN" "http://www.w3.org/TR/xhtml1/DTD/xhtml1-transitional.dtd">
    <html xmlns="http://www.w3.org/1999/xhtml">
    <head runat="server">
        <title>File Upload Control</title>
    </head>
    <body>
        <form id="form1" runat="server">
        <div>
        <asp:FileUpload  runat="server" ID="fuSample" />
        <asp:Button  runat="server" ID="btnUpload" Text="Upload" 
                onclick="btnUpload_Click" />
                <asp:Label runat="server" ID="lblMessage" Text=""></asp:Label>
        </div>
        </form>
    </body>
    </html>

using System;
using System.Collections.Generic;
using System.Linq;
using System.Web;
using System.Web.UI;
using System.Web.UI.WebControls;
public partial class Uploadfile : System.Web.UI.Page
{
    protected void Page_Load(object sender, EventArgs e)
    {
    }
    protected void btnUpload_Click(object sender, EventArgs e)
    {
        //Files is folder Name
        fuSample.SaveAs(Server.MapPath("Files") + "//" + fuSample.FileName);
        lblMessage.Text = "File Successfully Uploaded";
    }
}

then embed your aspx page in Html as follow,

<iframe height="40" width="700" src="Uploadfile.aspx">
</iframe>

now you can be able to upload your file from html itself,by using UploadFiles.aspx.

Solution 2:

Use code similar to this and then write it out to disk (using, say, FileStream)

HttpFileCollection MyFileCollection;
 HttpPostedFile MyFile;
 int FileLen;
 System.IO.Stream MyStream;

 MyFileCollection = Request.Files;
 MyFile = MyFileCollection[0];

 FileLen = MyFile.ContentLength;
 byte[] input = new byte[FileLen];

 // Initialize the stream.
 MyStream = MyFile.InputStream;

 // Read the file into the byte array.
 MyStream.Read(input, 0, FileLen);

http://msdn.microsoft.com/en-us/library/system.web.httppostedfile.inputstream%28VS.71%29.aspx