Any phrases like "What makes you tick?"

'What makes you tick', 'What turns you on', etc is a fairly common phrase construct in English.

You can modify the words used for their appropriateness in the conext - for example you wouldn't use 'what turns you on' in a formal context as it has sexual connotations.

Here's some suggestions:

What makes you tick - Fairly neutral, a bit casual.

What turns you on - Has sexual connotations, but not necessarily so. For example musicians might use this.

What floats your boat/What fills your sails/What lifts your rocket/What seasons your steak - I'm making these up to demonstrate that anything 'What verbs your noun' generally works, but might get a funny look. These are playful and informal.

What motivates you - Formal.

What you are passionate about - Slightly less formal.