A single word meaning “absolute control over something”

Solution 1:

I'd suggest you reconsider stranglehold, which actually is nowhere near as mild as you think.

stranglehold

  1. A grip around the neck of another person that can kill by asphyxiation if held for long enough.

  2. Complete or overwhelming control: in France, supermarkets have less of a stranglehold on food supplies ODO

If you're still not happy with it, consider:

chokehold

1: a hold that involves strong choking pressure applied to the neck of another

2: absolute dominance or control : had a chokehold on the city's finances M-W

throttlehold

A vicious, strangling, or stultifying control M-W

Solution 2:

Plenary.

It means unqualified or absolute control.

Solution 3:

You can consider the following set of words:

  • supremacy

  • authoritarian

  • totalitarian

supremacy (noun)

supreme authority or power.

authoritarian (adj.)

of or relating to a governmental or political system, principle, or practice in which individual freedom is held as completely subordinate to the power or authority of the state, centered either in one person or a small group that is not constitutionally accountable to the people.

totalitarian (adj.)

of or relating to a centralized government that does not tolerate parties of differing opinion and that exercises dictatorial control over many aspects of life.

[References - Dictionary.com]

Note that authoritarian and totalitarian are synonymous with neutral to negative connotation.

Solution 4:

dominion:

Oxford English Dictionaries:

    Sovereignty or control.
    ‘man’s attempt to establish dominion over nature’

American Heritage Dictionary:

    Control or the exercise of control; sovereignty: “The devil … has their souls in his possession, and under his dominion”  (Jonathan Edwards).
Collins English Dictionary:
    uncountable noun
    Dominion is control or authority.
    They truly believe they have dominion over us. [+ over]

Macmillan Dictionary:

    [uncountable] formal control, or the right to rule over something
    At that time the island was under foreign dominion.