Is it possible to both save Josie Thorpe and capture Zeke Sanders?
Try shooting him in the leg then going for a takedown.
As an alternative, if you originally ask Sarif for a stungun (non-lethal; short range), you should have no problems taking him out with it. You can fire much faster than Zeke. It's not like there's a shortage of lethal firearms (10mm Pistols, mostly) in the plant.
Yes you can. Here's an example shot to the log and double take down.
Caution... you will probably LOL extremely hard when watching.