A single word for a person who suffers great loss

Solution 1:

How about "destitute"

Phillip was left destitute as a result of the flood./ Phillip is now a destitute.

There is also "ruined"

Philip suffered great loss due to the flood. He is now ruined.

or

"Devastated"

Solution 2:

"Victim" is often used for everything from natural disasters to diseases to financial ruin.

Solution 3:

I'd suggest:

  • choker: an unfortunate person who is unable to perform effectively because of nervous tension or agitation.
  • Victim: One who is harmed by or made to suffer from an act, circumstance, agency, or condition.