Is it possible to run multiple instance of skype?

Solution 1:

I found it myself but forgot the site where I learned this, sorry :(

Run skype application from command line with argument /secondary

E.g.

In my case I executed "C:\Program Files\Skype\Phone\Skype.exe" /secondary

Solution 2:

Yes, run the first one on your computer and run the second one using the portable apps version:

http://portableapps.com/apps/internet/skype_portable