How to swap two DataFrame columns?

pandas has reindex method that does it. You just need to give a list with the column names in the order you wish:

columns_titles = ["B","A"]
df=df.reindex(columns=columns_titles)

Cheers

A slight variant on acushner's answer:

# get a list of the columns
col_list = list(df)
# use this handy way to swap the elements
col_list[0], col_list[1] = col_list[1], col_list[0]
# assign back, the order will now be swapped
df.columns = col_list

example:

In [39]:

df = pd.DataFrame({'a':randn(3), 'b':randn(3), 'c':randn(3)})
df
Out[39]:
          a         b         c
0 -0.682446 -0.200654 -1.609470
1 -1.998113  0.806378  1.252384
2 -0.250359  3.774708  1.100771
In [40]:

col_list = list(df)
col_list[0], col_list[1] = col_list[1], col_list[0]
df.columns = col_list
df
Out[40]:
          b         a         c
0 -0.682446 -0.200654 -1.609470
1 -1.998113  0.806378  1.252384
2 -0.250359  3.774708  1.100771

UPDATE

If you just want to change the column order without changing the column contents then you can reindex using fancy indexing:

In [34]:
cols = list(df)
cols[1], cols[0] = cols[0], cols[1]
cols

Out[34]:
['b', 'a', 'c']

In [35]:
df.ix[:,cols]

Out[35]:
          b         a         c
0 -0.200654 -0.682446 -1.609470
1  0.806378 -1.998113  1.252384
2  3.774708 -0.250359  1.100771

c = A.columns
A = A[c[np.r_[1, 0, 2:len(c)]]]

or, even easier:

A[[c[0], c[1]]] = A[[c[1], c[0]]]

*edit: fixed per Ivan's suggestions.