Do Crusades or Holy Wars Affect Infamy?

It appears Holy wars do affect infamy as would pressing any claim. However Crusades have no impact on infamy at all.

In my current game as the Emperor of Alba I declared a Holy war against the Sultan of Analusia for the Duchy of Beja in Portugal. Beja consists of 4 provinces and when I succeeded, enforcing my demands my infamy score increased by 33%. This led to to all of my neighbours (of mixed religions) within Hispania forming a coalition against me even though some helped me in my 'Just war'.

Note: There is an upcoming patch that will look to address the issue of unlikely coalitions ie. difference of religion and distance (so you should no longer see the Kingdom of Norway form a coalition against you with the Turkish Empire!)

Later in the game A crusade was called for the Kingdom of Anatolia. The Crusade was successful and I was the largest contributor gaining me the 20 provinces in Anatolia, which used to belong to the Byzantian Empire. This had no effect on my infamy what so ever.

Holy Wars, at least, do. As the Byzantine Emperor, I've lead a few holy wars against the Slavs. This has lead to a massive coalition, including most slavic kings (makes sense), but also Catholic Italy and the Muslim Abbassids.