Is a regular tessellation $\{p,q\}$ always possible on some closed surface $S$?
Solution 1:
This problem was solved in
Edmonds, Allan L.; Ewing, John H.; Kulkarni, Ravi S. Regular tessellations of surfaces and (p,q,2)-triangle groups. Ann. of Math. (2) 116 (1982), no. 1, 113–132.
From the MathReview of the paper:
The authors consider regular tessellations of type $(p,q)$ on a surface; a generalization of the Platonic solids. The parameter $p$ is the number of edges on each face while $q$ is the valence of each vertex. The main theorem states that as long as obvious necessary conditions, based on Euler's formula, are satisfied then a regular tessellation of type $(p,q)$ exists on a surface $M$. Furthermore, the edges can be geodesics and a classification of regular tessellations of type $(p,q)$ on $M$ is given based on $\pi_1(M)$. The main technique used to prove the theorem is construction of appropriate branched coverings over surfaces with irregular patterns.
The main result of their paper is Theorem 1:
Let $M$ be a closed surface and let $p, q, V, E, F$ be positive integers such that $$ V-E+F=\chi(M)$$ and $$ pF=2E=qV$$
Then: There exists a $(p, q)$-tessellation on $M$ consisting of $F$ $p$-sided faces, $E$ edges and $V$ vertices each of valence $q$; except when $M$ is the projective plane, $(p, q) = (3,3)$, $V = F = 2$, and $E = 3$.
Note that the above conditions are also necessary for the existence of a $(p,q)$-tessellation.
An important remark: For this theorem to hold, some of the polygonal faces $\sigma$ of the tessellation are allowed to be "singular'' in the sense that some of the edges of $\sigma$ are glued to each other on the surface $M$. A simple example of a singular face is the tessellation of the 2-torus which has unique 2-dimensional rectangular face, whose edges are identified in the standard manner. In other words, the CW complex underlying the tessellation, need not be regular.
Solution 2:
This is really an extended comment, rather than an answer, but it won't fit as a comment.
A little algebraic musing:
$$qV = 2E = pF$$ tells us that $$ pqV = 2pE\\ pq F = 2q E $$ so that $$ pq(V-E+F) = 2pE - pqE + 2q E = (2(p+q) - pq) E = \chi$$
So you don't really need to be given the Euler characteristic of $S$ -- you know that it's $(2(p+q) - pq) E$.
At this point the question can be divided into two parts: one where $S$ is orientable, one where it's not, for once you know an even number $\chi \le 2$, there's exactly one orientable and one nonorientable surface with that Euler characteristic.