Solution 1:

Your code work perfectly for me (I test it with Firefox, Chrome driver)

One thing I supect is excessive backslash(\) escape.

Try following:

driver.find_element_by_id("start-upload-button-single").click()
driver.find_element_by_css_selector('input[type="file"]').clear()
driver.find_element_by_css_selector('input[type="file"]').send_keys("C:\\Documents and Settings\\pcname\\Desktop\\ffdlt\\test.jpeg")

or

driver.find_element_by_id("start-upload-button-single").click()
driver.find_element_by_css_selector('input[type="file"]').clear()
driver.find_element_by_css_selector('input[type="file"]').send_keys(r"C:\Documents and Settings\pcname\Desktop\ffdlt\test.jpeg")

Solution 2:

Did you tried this single piece of code:

driver.find_element_by_css_selector("input[type=\"file\"]").send_keys("C:\\Documents and Settings\\pcname\\Desktop\\ffdlt\\test.jpeg")