How do you fight against grapplers?

A good starting strategy is to learn to bait the command throws and neutral jump.
Use a fast poke or a poke with some blockstun against command throw characters. If you connect, then follow it up with a combo. If you don't connect and instead are blocked then you should be safer.

I play Zangief frequently and that's generally what gets me. A good command throw player won't use that many command throws. It is the threat of the command throw that allows the player to force positioning. If I whiff on a command throw I will get punished hard.