Trigger Discipline Perk - Good for Snipers without VATS?

Solution 1:

High accuracy reduces bullet spread, but sniper rifles have very little spread when you fulfill its Strength/Guns requirements. They also have a good fire rate for a long range weapon, so you might prefer not to get this perk, which is better on weapons with high spread, like shotguns.

Just note that Fallout is not exactly a shooting game, and it might sometimes frustrate a player that chooses to avoid VATS. Think of VATS more like making the game be "turn-based" instead of a "cheat mode".