Would it be possible to use upcoming Intel's GPUs in desktops with amd CPU?
Solution 1:
Intel renders of the card, and "leaked images" of a so-called reference card depict a pci-e interface so "yes."
As far as the cards being motherboard chipset agnostic, I think it would be economic suicide for the product line to only work with intel-based boards, so I assume they will work.
They may have driver issues early on, but Intel has had for many years (IIRC) the largest GPU market, so I doubt there will be any show-stoppingly-bad driver-based problems.