Difficulty deleting registry keys under HKEY_Local_Machine\System\CurrentControlSet\Enum\USBSTOR

We are able to create and delete other registry keys but unable to delete subkeys under HKEY_Local_Machine\System\CurrentControlSet\Enum\USBSTOR. We've tried it on Windows 10 Enterprise where we are in the Administrators group as well as a command prompt and regedit in administrator mode. We have also tried it on Windows 10 Home editions but to no avail.

Has anyone else run into this? Anyone have a solution?

@John's link is my answer because that tool is amazing and will ultimately be part of my solution. thanks for all the advice!

https://www.sciencedirect.com/topics/computer-science/window-registry