No USB Keyboard or Mouse, Power Cuts off, Missing "Mouse and pointer" in Device Manager after Win10 Update

After 3 days troubleshooting and finding lots of poor people who didn't take a Restore Point before trying the RegKey hacks, I finally found a solution.

I ended up calling Microsoft support who went through many troubleshooting efforts with me. In the end, I needed to perform a full Windows upgrade to correct the issue.

Ref:

https://techcommunity.microsoft.com/t5/windows-10/pointing-devices-disappeared-from-within-device-manager/m-p/161142

Solution

Follow these steps to perform a full Windows upgrade, it does take a few hours though it's the only thing I've found that solves the problem and gets your USB Mouse, Keyboard, Joystick and etc back working again:

Take an OS image

1. Using a PS2 keyboard (or a USB female to PS2 male converter) navigate to Windows 10 download site.

2. Download and save the "Create Windows 10 installation media" on your computer.

3. When the download is completed, as a Administrator logged into your PC run the Media Creation Tool (MediaCreationTool21H1.exe).

4. Accept the license agreement.

5. Choose Create installation media for another PC & click Next.

6. At the next screen choose Next. *

7. At 'Choose which media to use' choose ISO file and click Next.

8. Select a location to save the 'Windows.iso' file and click Save (typically a 4.5GB file).

In place reinstall/upgrade using the OS image

1. Open Windows Explorer and navigate to the folder you saved the 'Windows.iso' file.

2. Right-click on the ISO file and select Open With > Windows Explorer.

3. Double click the setup.exe application.

4. At 'Ready to Install' screen, make sure that the "Keep personal files and Apps" option is selected and click Install.

5. Wait for the inplace reinstall/upgrade process to complete.

After it finishes you can plugin your USB Keyboard and Mouse and they will work!