Huh an empty folder that containers 42.8 GB?
Open Windows File Explorer, click on the View Tab, go to Options and make sure you are displaying Hidden Files.
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Also get a Trial License for Tree Size (Jam Software) and look at your drive with Tree Size. That will find large (and hidden) files and should expose a very large file. Local backup files are usually hidden and are large files.
I use Tree Size here and it is a good tool for this.