Run a wine application fullscreen on a single monitor from dual-monitor setup
There is an easy way to use a windowed mode in Wine:
Start Wine Configuration (winecfg)
Click on the ‘Graphics’ tab
Check ‘Emulate a virtual desktop’
Next to ‘Desktop size’ enter your exact screen resolution.
I found ~/.config/monitors.xml where you can set which monitor is the primary one (primary:yes) so wine displays Skyrim on my right monitor while my left one's still displaying unity and firefox :)