Upload file to FTP using C#

The existing answers are valid, but why re-invent the wheel and bother with lower level WebRequest types while WebClient already implements FTP uploading neatly:

using (var client = new WebClient())
{
    client.Credentials = new NetworkCredential(ftpUsername, ftpPassword);
    client.UploadFile("ftp://host/path.zip", WebRequestMethods.Ftp.UploadFile, localFile);
}

Easiest way

The most trivial way to upload a file to an FTP server using .NET framework is using WebClient.UploadFile method:

WebClient client = new WebClient();
client.Credentials = new NetworkCredential("username", "password");
client.UploadFile(
    "ftp://ftp.example.com/remote/path/file.zip", @"C:\local\path\file.zip");

Advanced options

If you need a greater control, that WebClient does not offer (like TLS/SSL encryption, ascii/text transfer mode, active mode, transfer resuming, progress monitoring, etc), use FtpWebRequest. Easy way is to just copy a FileStream to an FTP stream using Stream.CopyTo:

FtpWebRequest request =
    (FtpWebRequest)WebRequest.Create("ftp://ftp.example.com/remote/path/file.zip");
request.Credentials = new NetworkCredential("username", "password");
request.Method = WebRequestMethods.Ftp.UploadFile;  

using (Stream fileStream = File.OpenRead(@"C:\local\path\file.zip"))
using (Stream ftpStream = request.GetRequestStream())
{
    fileStream.CopyTo(ftpStream);
}

Progress monitoring

If you need to monitor an upload progress, you have to copy the contents by chunks yourself:

FtpWebRequest request =
    (FtpWebRequest)WebRequest.Create("ftp://ftp.example.com/remote/path/file.zip");
request.Credentials = new NetworkCredential("username", "password");
request.Method = WebRequestMethods.Ftp.UploadFile;  

using (Stream fileStream = File.OpenRead(@"C:\local\path\file.zip"))
using (Stream ftpStream = request.GetRequestStream())
{
    byte[] buffer = new byte[10240];
    int read;
    while ((read = fileStream.Read(buffer, 0, buffer.Length)) > 0)
    {
        ftpStream.Write(buffer, 0, read);
        Console.WriteLine("Uploaded {0} bytes", fileStream.Position);
    } 
}

For GUI progress (WinForms ProgressBar), see C# example at:
How can we show progress bar for upload with FtpWebRequest

Uploading folder

If you want to upload all files from a folder, see
Upload directory of files to FTP server using WebClient.

For a recursive upload, see
Recursive upload to FTP server in C#