Is there any disadvantage to asking for money?

For many of the side-missions during the game, you're given the option to ask something like "What's in it for me?", at which point the character you're speaking to (usually?) will offer you money.

Is there any disadvantage to doing this? Eg. does it affect the ending, or the Karma I receive, or can I lose some side-missions entirely?


Solution 1:

I haven't found any disadvantages but you often require something to be able to get more money. Such as high charisma, a lot of strength.