How to disable SHIFT + F10 keyboard shortcut in Windows 10?

Solution 1:

This does not appear to be a standard Windows shortcut. Standard Windows hotkeys, with the exception of the Ctrl+Alt+Del sequence, can be overridden by any application.

If you are on a laptop, the F-keys are often repurposed into media keys and you may need to additionally press an Fn key to get the F# function. See if there is an alternative function printed on the key, often in blue. You may be able to change the default (for the whole bar) in the firmware/BIOS settings. Some laptop models let you toggle the Fn-lock on the fly with combinations such as Fn+Esc.

If this is a Fn/media key issue, unfortunately the possibility and specific method of changing it will differ depending on the laptop. There are other somewhat clunkier ways (e.g. with AHK).