Has anyone used uwsgi nginx and django for a high-load environment?

We did some tests and it seems that uwsgi just answers with one concurrent request per process. This is because uwsgi DOESN'T fork off another process or thread. If make your application fully asynchronous (you have to use "yield" as often as possible), you could use uwsgi async feature. This should make your app a lot more scalable. As of trunk of uwsgi, threading is now supported with a max number of threads.