Detecting CGAssociateMouseAndMouseCursorPosition
Solution 1:
I dont know if this can help you
There is an option called Focus Follows Mouse
Focus Follows Mouse - The Mouse pointer will grab automatically change focus to a new window inisde this one app if you mouse over it, instead of having to click a window to get focus, then clicking to do something.
http://wineskin.urgesoftware.com/tiki-index.php?page=Manual+4.6+Advanced+-+Options