Rational solutions to $a+b+c=abc=6$
(Edit at the bottom.) Here is an elementary way (known to Fermat) to find an infinite number of rational points. From $a+b+c = abc = 6$, we need to solve the equation,
$$ab(6-a-b) = 6\tag1$$
Solving $(1)$ as a quadratic in $b$, its discriminant $D$ must be made a square,
$$D := a^4-12a^3+36a^2-24a = z^2$$
Using any non-zero solution $a_0$, do the transformation,
$$a=x+a_0\tag2$$
For this curve, let $a_0=2$, and we get,
$$x^4-4x^3-12x^2+8x+16$$
Assume it to be a square,
$$x^4-4x^3-12x^2+8x+16 = (px^2+qx+r)^2$$
Expand, then collect powers of $x$ to get the form,
$$p_4x^4+p_3x^3+p_2x^2+p_1x+p_0 = 0$$
where the $p_i$ are polynomials in $p,q,r$. Then solve the system of three equations $p_2 = p_1 = p_0 = 0$ using the three unknowns $p,q,r$. One ends up with,
$$105/64x^4+3/8x^3=0$$
Thus, $x =-16/35$ or,
$$a = x+a_0 = -16/35+2 = 54/35$$
and you have a new rational point,
$$a_1 = 54/35 = 6\times 3^{\color{red}2}/35$$
Use this on $(2)$ as $x = y+54/35$ and repeat the procedure. One gets,
$$a_2 = 6\times 4286835^{\color{red}2}/37065988023371$$
Again using this on $(2)$, we eventually have,
$$\small {a_3 = 6\times 11838631447160215184123872719289314446636565357654770746958595}^{\color{red}2} /d\quad$$
where the denominator $d$ is a large integer too tedious to write.
Conclusion: Starting with a "seed" solution, just a few iterations of this procedure has yielded $a_i$ with a similar form $6n^{\color{red}2}/d$ that grow rapidly in "height". Heuristically, it then suggests an infinite sequence of distinct rational $a_i$ that grow in height with each iteration.
$\color{blue}{Edit}$: Courtesy of Aretino's remark below, then another piece of the puzzle was found. We can translate his recursion into an identity. If,
$$a^4-12a^3+36a^2-24a = z^2$$
then subsequent ones are,
$$v^4-12v^3+36v^2-24v = \left(\frac{12\,e\,g\,(e^2+3f^2)}{(e^2-f^2)^2}\right)^2$$
where,
$$\begin{aligned} v &=\frac{-6g^2}{e^2-f^2}\\ \text{and,}\\ e &=\frac{a^3-3a^2+3}{3a}\\ f &=\frac{a^3-6a^2+9a-6}{z}\\ g &=\frac{a^3-6a^2+12a-6}{z} \end{aligned}$$
Starting with $a_0=2$, this leads to $v_1 = 6\times 3^2/35$, then $v_2 = 6\times 4286835^2/37065988023371$, ad infinitum. Thus, this is an elementary demonstration that there an infinite sequence of rational $a_i = v_i$ without appealing to elliptic curves.
More generally, suppose for some $S,P$ we're given a rational solution $(a_0,b_0,c_0)$ of the Diophantine equation $$ E = E_{S,P}: \quad a+b+c = S, \ \ abc = P. $$ Then, as long as $a,b,c$ are pairwise distinct, we can obtain a new solution $(a_1,b_1,c_1)$ by applying the transformation $$ T\bigl((a,b,c)\bigr) = \left( -\frac{a(b-c)^2}{(a-b)(a-c)} \, , -\frac{b(c-a)^2}{(b-c)(b-a)} \, , -\frac{c(a-b)^2}{(c-a)(c-b)} \right). $$ Indeed, it is easy to see that the coordinates of $T(a,b,c)$ multiply to $abc$; that they also sum to $a+b+c$ takes only a bit of algebra. (This transformation was obtained by regarding $abc=P$ as a cubic curve in the plane $a+b+c=S$, finding the tangent at $(a_0,b_0,c_0)$, and computing its third point of intersection with $abc=P$; see picture and further comments below.) We can then repeat the procedure, computing $$ (a_2,b_2,c_2) = T\bigl((a_1,b_1,c_1)\bigr), \quad (a_3,b_3,c_3) = T\bigl((a_2,b_2,c_2)\bigr), $$ etc., as long as each $a_i,b_i,c_i$ are again pairwise distinct. In our case $S=P=6$ and we start from $(a_0,b_0,c_0) = (1,2,3)$, finding $(a_1,b_1,c_1) = (-1/2, 8, -3/2)$, $(a_2,b_2,c_2) = (-361/68, -32/323, 867/76)$, $$ (a_3,b_3,c_3) = \left( \frac{79790995729}{9885577384}\, ,\ -\frac{4927155328}{32322537971}\, ,\ -\frac{9280614987}{24403407416}\, \right), $$ "etcetera".
As with the recursive construction given by Tito Piezas III, the construction of $T$ via tangents to a cubic is an example of a classical technique that has been incorporated into the modern theory of elliptic curves but does not require explicit delving into this theory. Also as with TPIII's construction, completing the proof requires showing that the iteration does not eventually cycle. We do this by showing that (as suggested by the first three steps) the solutions $(a_i,b_i,c_i)$ get ever more complicated as $i$ increases.
We measure the complexity of a rational number by writing it as $m/n$ in lowest terms and defining a "height" $H$ by $H(m/n) = \sqrt{m^2+n^2}$. Using the defining equations of $E_{S,P}$, we eliminate $b,c$ from the formula for the first coordinate of $T\bigl( (a,b,c) \bigr)$, and likewise for each of the other two coordinates, finding that $$ T\bigl( (a,b,c) \bigr) = (t(a),t(b),t(c)) \bigr) $$ where $$ t(x) := -\frac{x^2(x-S)^2 - 4Px}{x^2(2x-S)+P}. $$ We find that the numerator and denominator are relatively prime as polynomials in $x$, unless $P=0$ or $P=(S/3)^3$, when $E_{S,P}$ is degenerate (obviously so if $P=0$, and with an isolated double point at $a=b=c=S/3$ if $P=(S/3)^3$). Thus $t$ is a rational function of degree $4$, meaning that $$ t(m/n) = \frac{N(m,n)}{D(m,n)} $$ for some homogeneous polynomials $N,D$ of degree $4$ without common factor. We claim:
Proposition. If $f=N/D$ is a rational function of degree $d$ then there exists $c>0$ such that $H(t(x)) \geq c H(x)^d$ for all $x$.
Corollary: If $d>1$ and a sequence $x_0,x_1,x_2,x_3,\ldots$ is defined inductively by $x_{i+1} = f(x_i)$, then $H(x_i) \rightarrow \infty$ as $i \rightarrow \infty$ provided some $H(x_i)$ is large enough, namely $H(x_i) > c^{-1/(d-1)}$.
Proof of Proposition: This would be clear if we knew that the fraction $f(m/n) = N(m,n)/D(m,n)$ must be in lowest terms, because then we could take $$ c = c_0 := \min_{m^2+n^2 = 1} \sqrt{N(m,n)^2 + D(m,n)^2}. $$ (Note that $c_0$ is strictly positive, because it is the minimum value of a continuous positive function on the unit circle, and the unit circle is compact.) In general $N(m,n)$ and $D(m,n)$ need not be relatively prime, but their gcd is bounded above: because $N,D$ have no common factor, they have nonzero linear combinations of the form $R_1 m^{2d}$ and $R_2 n^{2d}$, and since $\gcd(m^{2d},n^{2d}) = \gcd(m,n)^{2d} = 1$ we have $$ \gcd(N(m,n), D(m,n)) \leq R := \text{lcm} (R_1,R_2). $$ (In fact $R = \pm R_1 = \pm R_2$, the common value being $\pm$ the resultant of $N$ and $D$; but we do not need this.) Thus we may take $c = c_0/R$, QED.
For our degree-$4$ functions $t$ associated with $E_{S,P}$ we compute $R = P^2 (27P-S^3)^2$, which is $18^4$ for our $S=P=6$; and we calculate $c_0 > 1/12$ (the minimum occurs near $(.955,.3)$). Hence the sequence of solutions $(a_i,b_i,c_i)$ is guaranteed not to cycle once some coordinate has height at least $(12 \cdot 18^4)^{1/3} = 108$. This already happens for $i=2$, so we have proved that $E_{6,6}$ has infinitely many rational solutions. $\Box$
The same technique works with TPIII's recursion, which has $d=9$.
The following Sage plot shows:
in $\color{blue}{\text{blue}}$, the curve $E_{6,6}$, projected to the $(a,b)$ plane (with both coordinates in $[-6,12]$);
in $\color{gray}{\text{gray}}$, the asymptotes $a=0$, $b=0$, and $c=0$;
and in $\color{orange}{\text{orange}}$, $\color{red}{\text{red}}$, and $\color{brown}{\text{brown}}$, the tangents to the curve at $(a_i,b_i,c_i)$ that meet the curve again at $(a_{i+1},b_{i+1},c_{i+1})$, for $i=0,1,2$:
(source: harvard.edu)
Further solutions can be obtained intersecting $E$ with the line joining two non-consecutive points; this illustrated by the dotted $\color{green}{\text{green}}$ line, which connects the $i=0$ to the $i=2$ point, and meets $E$ again in a point $(20449/8023, 25538/10153, 15123/16159)$ with all coordinates positive.
In the modern theory of elliptic curves, the rational points (including any rational "points at infinity", here the asymptotes) form an additive group, with three points adding to zero iff they are the intersection of $E$ with a line (counted with multiplicity). Hence if we denote our initial point $(1,2,3)=(a_0,b_0,c_0)$ by $P$, the map $T$ is multiplication by $-2$ in the group law, so the $i$-th iterate is $(-2)^i P$, and $(20449/8023, 25538/10153, 15123/16159)$ is $-(P+4P) = -5P$. Cyclic permutations of the coordinates is translation by a 3-torsion point (indeed an elliptic curve has a rational 3-torsion point iff it is isomorphic with $E_{S,P}$ for some $S$ and $P$), and switching two coordinates is multiplication by $-1$. The iteration constructed by Tito Piezas III is multiplication by $\pm 3$ in the group law; in general, multiplication by $k$ is a rational function of degree $k^2$.
We just need to prove that for infinite values of $q\in\mathbb{Q}$ the polynomial $$ p(x)=x^3-6x^2+qx-6 $$ completely splits over $\mathbb{Q}$. That is the same as requiring that $$ p(x+2) = x^3+(q-12)x+(2q-22) $$ completely splits over $\mathbb{Q}$. Assuming that $u,w,w$ are the roots of the above polynomial, then $u+v+w=0$, $uv+uw+vw=(q-12)$, $uvw=22-2q$, so we just need to show that there is an aperiodic rational map $\phi:(u,v)\to(\tilde{u},\tilde{v})$ that preserves: $$-2=uvw+2(uv+uw+vw) = -2u^2-2uv-2v^2-u^2 v- v^2 u$$ but honestly I do not know how to find it without invoking the group structure for an elliptic curve.
A rational triple $(a,b,c)$ satisfies $a+b+c=abc=6$ if and only if $$c=6-a-b\qquad\text{ and }\qquad ab(6-a-b)=6,$$ where the latter is equivalent to $$a\cdot b^2+a(a-6)\cdot b+6=0,$$ which shows that $b=\tfrac{6-a}{2}\pm\tfrac{1}{2a}\sqrt{a^2(a-6)^2-24a}$. Because $a$ and $b$ are rational, the expression $$a^2(a-6)^2-24a=a^4-12a^3+36a^2-24a,$$ must be a rational square. So it suffices to show that the curve $$x^4-12x^3+36x^2-24x=y^2,$$ has infinitely many rational points. I don't see an elementary way to do so. It may be worth noting that it can be seen to have the rational points $(0,0)$ and $(2,2)$.
A blunt way to finish is to note that this curve is birational to the elliptic curve $$y^2=x^3-9x+9,$$ of positive rank, so indeed there are infinitely many rational solutions.