Ubuntu mate shortcuts for area-screenshot and change-layout

To disable interactive area screenshot you have to edit the command which executes on Shift+PrintScreen by using command below:

gsettings set org.mate.Marco.keybinding-commands command-2 "/bin/sh -c 'sleep .1;mate-screenshot --area'"

Reverting to defaults is possible by

gsettings set org.mate.Marco.keybinding-commands command-2 "mate-screenshot --area --interactive"

If you do not want to change the command for Shift+PrintScreen, add your own custom keyboard shortcut for custom /bin/sh -c 'sleep .1;mate-screenshot --area' command from Keyboard Shortcuts (or run mate-keybinding-properties directly).

Then about keyboard layouts. You have to open MATE Keyboard Preferences from MATE Control Center (or run mate-keyboard-properties directly) and then add keyboard layouts on the Layouts tab, click Options to set Switching to another layout to the needed value like Alt+Shift. This will allow you to switch between keyboard layouts by the specified shortcut in cycle.

Note: if you have a problem with Ctrl+Shift+other_key interference, then you have to add my PPA to the system (see this answer for details).