Windows 10 not showing files and folders in E drive

Solution 1:

Showing Hidden and Protected System Files with File Explorer

From File Explorer, click the View tab. From the Options drop down select Change folder and search options. When the Folder Options window opens, select the View tab from there, and then check Show hidden files, folders, and drive, uncheck Hide empty drives, and uncheck Hide protected operating system files, press Apply, Ok and now check the "E" drive from File Explorer and you can do with them whatever you want at this point for your needs.

Solution 2:

There are many possibilities for this happening. But as one of them is a damaged file-system, I would advise to first take a backup of the files. Since you cannot use Windows, use live Linux to copy all the data to an external media.

Here are some possible actions :

Reset folder and file attributes

Open an elevated Command Prompt (cmd) and enter the command E:, followed by the command dir /ah. If this shows your folders, then enter the following command and wait for it to finish:

attrib -r -a -s -h

Check disk

In the same Command Prompt instance, enter the command :

chkdsk E:

This will only check the disk. If it finds errors, then enter the following command to fix :

chkdsk E: /f

Take Ownership

The folders on the drive might have changed their owning account. To restore yourself as the owner :

• In Windows Explorer, right-click E and choose Properties
• Click the Security tab
• Click the Advanced button
• If the owner is you or Administrators, all is OK
• Otherwise, click the Change button
• Click the Advanced button
• Click Find Now
• Double-click on Administrators (or Users for all users)
• Click OK
• Check "Replace owner on subcontainers and objects"
• Click Apply

Reset permissions

• As above, go to Properties and then to the Security tab
• Click Edit
• Click Administrators
• If Full control is checked, stop
• Otherwise, check it and click Apply
• Repeat for Users

Disable Fast Startup

Some reports blame it for strange happening with the file system. See this article:
Turn On or Off Fast Startup in Windows 10.